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008 201106s2021 flu b 001 0 eng
010 _a 2020050614
020 _a9781138597327
020 _z9780429486951
040 _aDLC
_beng
_erda
_cDLC
042 _apcc
082 0 0 _a570.113
_223
_bRAM
100 1 _aRaman, Karthik,
245 1 3 _aAn introduction to computational systems biology :
_bsystems-level modelling of cellular networks /
_cKarthik Raman.
250 _aFirst edition.
260 _aBoca Raton, FL :
_bCRC Press,
_c2021.
300 _a336 pages :
_billustrations (black and white) ;
_c24 cm.
440 _aChapman & Hall/CRC computational biology series
505 _tIntroduction to modelling
_tIntroduction to graph theory
_tStructure of networks
_tApplications of network biology
_tIntroduction to dynamic modelling
_tParameter estimation
_tDiscrete dynamic models: Boolean networks
_tIntroduction to constraint-based modelling
_tExtending constraint-based approaches
_tPerturbations to metabolic networks
_tModelling cellular interactions
_tDesigning biological circuits
_tRobustness and evolvability of biological systems
_tEpilogue: The Road Ahead
520 _a"This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks-a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. The book is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others"--
650 0 _aSystems biology.
650 0 _aBiological systems
650 0 _aMolecular biology
650 0 _aComputational biology.
942 _2ddc
_cBK
100 1 _eauthor.
263 _a1111
264 1 _aBoca Raton, FL :
_bCRC Press,
_c2021.
336 _atext
_btxt
_2rdacontent
337 _aunmediated
_bn
_2rdamedia
338 _avolume
_bnc
_2rdacarrier
490 0 _aChapman & Hall/CRC computational biology series
504 _aIncludes bibliographical references and index.
520 _cProvided by publisher.
650 0 _xComputer simulation.
650 0 _xData processing.
906 _a0
_bvip
_corignew
_d1
_eecip
_f20
_gy-gencatlg